A Higher Standard for Recombinant Protein Material in Drug Discovery

QualityPlus is the CrystalsFirst standard for recombinant proteins developed for demanding biophysical, structural, and functional studies in drug discovery. Proteins follow a rigorous quality control for the properties, purity, homogeneity, and batch-to-batch consistency, which helps drug discovery campaigns to generate reproducible and reliable data.

Exceptional Purity

Our proteins undergo stringent, multi-step chromatographic purification, eliminating impurities that can interfere with binding assays and structural studies. The high purity is crucial for obtaining reproducible and reliable data of protein-ligand binding and high-quality crystal diffraction data sets.

High Homogeneity

Structural and conformational homogeneity are essential for consistent experimental performance. Through optimized production and analytical assessment, including SEC polishing and Dynamic Light Scattering, we provide proteins suited for demanding structural and biophysical applications.

Lot-to-Lot Consistency

Rigorous Quality Control of each protein batch by Dynamic Light Scattering, nanoDSF and crystallization ensures reliable reproducibility across different batches, helping reduce variability across repeat studies and long-term projects.

Ready-to-Use Concentration

Supplied at concentrations ideal for immediate use in crystallization or biophysical campaigns.